The Datacenter Edition of Windows Server 2022 is a step above the Standard Edition. Although Hotpatching is not available here as well, however, it includes Software-defined Networking. The Datacenter edition offers unlimited Storage Replica and includes the Storage Spaces Direct feature as well. Inherited activation can be done as a host or a guest.
A step above the Standard Edition, Datacenter Edition offers unlimited Virtual machines, plus one Hyper-V host per license along with unlimited Virtual OSE/Hyper-V isolated Containers.
Missing in Standard, Host Guardian Hyper-V Support is available for Datacenter Edition. Also, there is support for Shielded Virtual Machines which is not available in Standard Edition.